SanareLab
Blue Essence – Methylene Blue 10 mg, USP Grade, Liquid Drops, 60 mL (2 fl oz)
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Each serving (20 drops / 1 mL) delivers 10 mg of USP-grade Methylene Blue in a precise 1% liquid solution. Clean formula: purified water + vegetable glycerin. 60 mL bottle provides 50 servings with an included glass dropper for accurate daily dosing. Non-GMO, gluten-free, vegan. Made in a GMP-certified, FDA-registered U.S. facility.
10 mg
USP-grade MB per serving
1%
Concentration solution
50
Servings per bottle
USA
GMP & FDA-registered
What Research Shows
Mitochondrial Output
+70%
Low-dose MB increased cellular oxygen consumption by up to 70% and ATP production by ~30% in cell culture and animal models
Memory Retrieval
+7%
Single low-dose MB improved correct memory retrieval by 7% vs. placebo in a double-blind RCT with 26 healthy adults (Radiology, 2016)
Brain Blood Flow
+18%
Global cerebral blood flow increased 18% after MB administration, with significant regional increases in hippocampus and prefrontal cortex (PET/MRI)
Neuroprotection
EC₅₀ 20 nM
MB provided neuroprotection against glutamate toxicity at nanomolar concentrations, functioning as a regenerable mitochondrial antioxidant (PLoS ONE)
Brain Connectivity
fMRI ↑
Single low-dose MB increased resting-state functional connectivity in hippocampus, prefrontal, parietal, and insular cortex (double-blind human fMRI trial)
MCI Progression
-48%
Patients with MCI receiving low-dose MB (16 mg/day) had 48% lower incidence of progression to dementia over 12 months vs. control (Phase III RCT)
How Methylene Blue Works
Methylene Blue acts as an alternative electron carrier in the mitochondrial electron transport chain. It accepts electrons from NADH and delivers them directly to cytochrome c, bypassing Complex I-III — increasing oxygen consumption and ATP production while reducing oxidative stress. In its reduced form (leuco-MB), it functions as a direct free radical scavenger, then recycles back to its oxidized form — creating a self-renewing antioxidant cycle within mitochondria. MB crosses the blood-brain barrier easily, concentrating in neuronal mitochondria.
Dosing Guide
Blue Essence is a 1% concentration solution — each drop delivers approximately 0.5 mg of Methylene Blue. Adjust your dose precisely using the included glass dropper:
Key Areas of Support
What's Inside
- Methylene Blue USP — 10 mg per serving (1 mL), pharmaceutical-grade purity
- Purified Water — clean solvent base
- Vegetable Glycerin — natural stabilizer, smooth consistency
- 1% solution concentration for precise dosing
- No artificial colors, fillers, or preservatives
- Non-GMO, gluten-free, vegan
- Every batch lab-tested for identity, potency, and contaminants
Suggested Use & Storage
Shake well. Take 20 drops (1 mL) in water or juice in the morning, or as directed by your healthcare provider. A temporary change in urine color is normal and expected — this is a harmless, well-documented effect of Methylene Blue.
Store in a cool, dry place away from direct sunlight. Keep the bottle tightly closed when not in use. Keep out of reach of children.
Frequently Asked Questions
Why choose liquid drops over capsules?
Liquid drops allow precise dose adjustment — from 0.5 mg (1 drop) to 30 mg (60 drops) — unlike fixed-dose capsules. The 1% concentration makes it easy to titrate your ideal serving. Liquid format also offers faster absorption via sublingual or oral delivery.
What is USP-grade Methylene Blue?
USP (United States Pharmacopeia) grade means the compound meets strict pharmaceutical purity standards — free from contaminants and heavy metals, with verified identity and potency. This is critical for MB, as industrial-grade variants may contain harmful impurities.
Why does my urine turn blue/green?
This is completely normal and harmless. Methylene Blue is a water-soluble dye that is excreted through urine. The color change is temporary and stops after discontinuation. It actually confirms that MB is being properly absorbed and metabolized.
Are there any drug interactions?
Do not use if taking SSRIs or MAOIs. MB is a potent reversible inhibitor of monoamine oxidase A (MAO-A). Combined with serotonergic medications, it may cause serotonin syndrome. Not intended for pregnant or nursing women. Consult your healthcare provider if you have existing medical conditions.
Can I combine it with other supplements?
MB pairs well with mitochondrial support supplements. Consider combining with NAD+ Nicotinamide Riboside for cellular energy support, or Curcumin Turmeric for antioxidant synergy.
Warning: Do not use if taking SSRIs or MAOIs. Not intended for use by pregnant or nursing women. If you are taking any medications or have a medical condition, consult your healthcare professional before use. Discontinue use if any adverse reactions occur and seek medical advice. Keep out of reach of children.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Contact support@sanarelab.com for questions.
